A fluorescent probe for zinc ions based on N-methyltetraphenylporphine with high selectivity

Spectrochim Acta A Mol Biomol Spectrosc. 2009 Jan;71(5):1683-7. doi: 10.1016/j.saa.2008.06.020. Epub 2008 Jul 1.

Abstract

N-methyl-alpha,beta,gamma,delta-tetraphenylporphine (NMTPPH) has been used to detect trace amount of zinc ions in ethanol-water solution by fluorescence spectroscopy. The fluorescent probe undergoes a fluorescent emission intensity enhancement upon binding to zinc ions in EtOH/H(2)O (1:1, v/v) solution. The fluorescence enhancement of NMTPPH is attributed to the 1:1 complex formation between NMTPPH and Zn(II) which has been utilized as the basis for the selective detection of Zn(II). The linear response range covers a concentration range of Zn(II) from 5.0x10(-7) to 1.0x10(-5)mol/L and the detection limit is 1.5x10(-7)mol/L. The fluorescent probe exhibits high selectivity over other common metal ions except for Cu(II).

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fluorescent Dyes / pharmacology*
  • Ions / chemistry
  • Metalloporphyrins / chemistry
  • Models, Biological
  • Porphyrins / chemistry
  • Substrate Specificity
  • Zinc / analysis*
  • Zinc / chemistry

Substances

  • Fluorescent Dyes
  • Ions
  • Metalloporphyrins
  • N-methyltetraphenylporphine
  • Porphyrins
  • tetraphenylporphine
  • Zinc