Abstract
The BioRad BioPlex 2200 Vasculitis kit demonstrates excellent relative sensitivity and relative specificity for the semi-quantitative detection of IgG autoantibodies to MPO, PR3 and GBM. The fully-automated platform simultaneously measures three analytes in a single tube, offering superior advantage in speed and ease of use over current assays. The availability of a fully-automated platform with 24-hour availability for these three antibodies may be of considerable value in the differential diagnosis of patients with rapidly progressive glomerulonephritis.
MeSH terms
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Antibodies, Antineutrophil Cytoplasmic / immunology*
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Diagnosis, Differential
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Diagnostic Equipment
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Enzyme-Linked Immunosorbent Assay
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Flow Cytometry
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Glomerulonephritis / diagnosis*
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Glomerulonephritis / immunology
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Granulocyte Colony-Stimulating Factor / immunology*
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Humans
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Immunomagnetic Separation
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Interleukin-3 / immunology*
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Peroxidase / immunology*
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Reagent Kits, Diagnostic*
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Recombinant Fusion Proteins / immunology*
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Recombinant Proteins
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Reproducibility of Results
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Sensitivity and Specificity
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Vasculitis / diagnosis*
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Vasculitis / immunology
Substances
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Antibodies, Antineutrophil Cytoplasmic
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Interleukin-3
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Reagent Kits, Diagnostic
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Recombinant Fusion Proteins
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Recombinant Proteins
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myelopoietin
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Granulocyte Colony-Stimulating Factor
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Peroxidase