Unexpected discovery of 2 cases of hepatocyte nuclear factor 1alpha-mutated infracentimetic adenomatosis

World J Gastroenterol. 2008 Aug 14;14(30):4830-3. doi: 10.3748/wjg.14.4830.

Abstract

We present 2 cases of hepatocyte nuclear factor 1alpha (HNF1alpha)-mutated adenomatosis, discovered for reasons unrelated to this disease, and identified using immunohistochemical methods. These new tools may further our understanding of the link between adenomas/adenomatosis subtypes and their complications, and their association with other abnormalities.

Publication types

  • Case Reports

MeSH terms

  • Adenoma, Liver Cell / genetics*
  • Adenoma, Liver Cell / pathology
  • Adult
  • DNA Mutational Analysis
  • Female
  • Gene Expression Regulation, Neoplastic*
  • Hepatocyte Nuclear Factor 1-alpha / genetics*
  • Humans
  • Immunohistochemistry
  • Incidental Findings*
  • Liver Neoplasms / genetics*
  • Liver Neoplasms / pathology
  • Middle Aged
  • Mutation*

Substances

  • Hepatocyte Nuclear Factor 1-alpha