Creation of systematic guidelines for clinical use in diabetes emerges from the necessity of treatment quality improvement. Recommendations are validated according to current clinical data. Strength of recommendations is established based on systematic review of studies, each of which is of certain category due to its methodology. There exists an organization called Grades of Recommendation, Assessment, Development and Evaluation, the aim of which is to create homogenous quality assessment system and category of recommendations. It will be accomplished through the evaluation of data quality, creation of recommendations and defining its strength. The recommendations of NICE, ADA and PTD (Polish Diabetes Association) are very similar with regard to the significance of education of patients as well as performing frequent screening for late complications of diabetes and autoimmunological diseases. The recommendations are different when it comes to target glycemia (fasting blood glycemia, postprandial glycemia and HbA1c), especially depending on patient's age. The knowledge on the principles of recommendations creation and the symbols of recommendation's strength are essential for medical doctors taking care of diabetic patients while choosing the treatment method as well as the individualized approach towards every patient with diabetes.