Stimulation of human mast cells by activated T cells leads to N-Ras activation through Ras guanine nucleotide releasing protein 1

J Allergy Clin Immunol. 2008 Dec;122(6):1222-5. doi: 10.1016/j.jaci.2008.07.024. Epub 2008 Aug 28.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Coculture Techniques
  • DNA-Binding Proteins / immunology*
  • DNA-Binding Proteins / metabolism
  • Guanine Nucleotide Exchange Factors / immunology*
  • Guanine Nucleotide Exchange Factors / metabolism
  • Humans
  • Isoenzymes
  • Jurkat Cells
  • Lymphocyte Activation / immunology*
  • MAP Kinase Signaling System / immunology*
  • Mast Cells / enzymology
  • Mast Cells / immunology*
  • Oncogene Protein p21(ras) / immunology*
  • Oncogene Protein p21(ras) / metabolism
  • T-Lymphocytes / enzymology
  • T-Lymphocytes / immunology*

Substances

  • DNA-Binding Proteins
  • Guanine Nucleotide Exchange Factors
  • Isoenzymes
  • RASGRP1 protein, human
  • Oncogene Protein p21(ras)