Abstract
A combination of "chiron" and "asymmetric" approaches is utilized to construct the southern (C 9-C 25) region of marine natural product spirastrellolide B. The key functionalities are derived from d-glucose and Sharpless asymmetric epoxidation and dihydroxylation.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Biological Products / chemical synthesis
-
Biological Products / chemistry
-
Macrolides / chemical synthesis*
-
Macrolides / chemistry
-
Spiro Compounds / chemical synthesis*
-
Spiro Compounds / chemistry
Substances
-
Biological Products
-
Macrolides
-
Spiro Compounds
-
spirastrellolide B
-
spirastrellolide C