Abstract
Sand fly-parasite and sand fly-host interactions play an important role in the transmission of leishmaniasis. Vector molecules relevant for such interactions include midgut and salivary proteins. These potential targets for interruption of propagation of Leishmania parasites have been poorly characterized. Transcriptomic analysis has proven to be an effective tool for identification of new sand fly molecules, providing exciting new insights into vector-based control strategies against leishmaniasis.
Publication types
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Research Support, N.I.H., Intramural
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Review
MeSH terms
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Animals
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Gene Expression Profiling*
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Host-Parasite Interactions*
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Insect Proteins / genetics
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Insect Proteins / metabolism*
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Insect Vectors / parasitology
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Leishmania / physiology*
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Leishmaniasis / parasitology
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Leishmaniasis / prevention & control*
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Leishmaniasis / transmission
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Psychodidae / metabolism
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Psychodidae / parasitology*
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Salivary Proteins and Peptides / genetics
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Salivary Proteins and Peptides / metabolism
Substances
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Insect Proteins
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Salivary Proteins and Peptides