Acute hemorrhagic edema of infancy: report of 4 cases and review of the current literature

Clin Pediatr (Phila). 2009 Apr;48(3):323-6. doi: 10.1177/0009922808323113. Epub 2008 Sep 4.

Abstract

Acute hemorrhagic edema of infancy (AHEI) is a cutaneous leukocytoclastic vasculitis that usually occurs in children younger than 2 years of age. It is a rare disease characterized by mild fever, a violent onset of hemorrhagic skin lesions, and edema usually followed by a spontaneous and complete recovery. Although the etiology is unknown, AHEI often follows infections, drug treatment, or vaccination. In the present report, the authors describe 4 cases of AHEI and review the relevant literature.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acute Disease
  • Analgesics, Non-Narcotic / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Child, Preschool
  • Edema / diagnosis*
  • Edema / etiology
  • Female
  • Hemorrhage / diagnosis*
  • Hemorrhage / etiology
  • Humans
  • Infant
  • Male
  • Skin / pathology
  • Skin Diseases / diagnosis*
  • Skin Diseases / drug therapy*
  • Skin Diseases / etiology
  • Vasculitis, Leukocytoclastic, Cutaneous / complications
  • Vasculitis, Leukocytoclastic, Cutaneous / diagnosis*
  • Vasculitis, Leukocytoclastic, Cutaneous / drug therapy*

Substances

  • Analgesics, Non-Narcotic
  • Anti-Bacterial Agents