Statins alone are ineffective in cerebral malaria but potentiate artesunate

Antimicrob Agents Chemother. 2008 Nov;52(11):4203-4. doi: 10.1128/AAC.00513-08. Epub 2008 Sep 8.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antimalarials / administration & dosage*
  • Artemisinins / administration & dosage*
  • Artesunate
  • Atorvastatin
  • Disease Models, Animal
  • Drug Synergism
  • Fatty Acids, Monounsaturated / administration & dosage
  • Fluvastatin
  • Heptanoic Acids / administration & dosage
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage*
  • Indoles / administration & dosage
  • Malaria, Cerebral / drug therapy*
  • Malaria, Cerebral / parasitology
  • Malaria, Falciparum / drug therapy*
  • Malaria, Falciparum / parasitology
  • Mice
  • Neuroprotective Agents / administration & dosage*
  • Pravastatin / administration & dosage
  • Pyrroles / administration & dosage
  • Simvastatin / administration & dosage

Substances

  • Antimalarials
  • Artemisinins
  • Fatty Acids, Monounsaturated
  • Heptanoic Acids
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Indoles
  • Neuroprotective Agents
  • Pyrroles
  • Fluvastatin
  • Artesunate
  • Atorvastatin
  • Simvastatin
  • Pravastatin