Lack of increase in time to blood culture positivity in a patient with persistent methicillin-resistant Staphylococcus aureus bacteremia predicts failure of antimicrobial therapy

Chun-Hsing Liao; Yu-Tsung Huang; Fang-Yeh Chu; Tsui-Hsien Lin; Po-Ren Hsueh

Lack of increase in time to blood culture positivity in a patient with persistent methicillin-resistant Staphylococcus aureus bacteremia predicts failure of antimicrobial therapy

J Microbiol Immunol Infect. 2008 Aug;41(4):355-7.

Authors

Chun-Hsing Liao¹, Yu-Tsung Huang, Fang-Yeh Chu, Tsui-Hsien Lin, Po-Ren Hsueh

Affiliation

¹ Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan.

PMID: 18787745

Abstract

Time to positivity is an available parameter in automated blood culture systems. We report a patient with persistent methicillin-resistant Staphylococcus aureus bacteremia who received various regimens for treatment of methicillin-resistant S. aureus, and demonstrate that monitoring of the time to positive blood culture might be helpful in the early recognition of treatment failure.

Publication types

Case Reports

MeSH terms

Acetamides / therapeutic use
Aged
Anti-Bacterial Agents / therapeutic use*
Bacteremia / drug therapy
Bacteremia / microbiology*
Blood / microbiology*
Catheters, Indwelling / microbiology
Female
Humans
Linezolid
Methicillin-Resistant Staphylococcus aureus / isolation & purification*
Oxazolidinones / therapeutic use
Staphylococcal Infections / drug therapy
Staphylococcal Infections / microbiology*
Time Factors
Treatment Failure
Vancomycin / therapeutic use

Substances

Acetamides
Anti-Bacterial Agents
Oxazolidinones
Vancomycin
Linezolid