Abstract
A series of twenty six arylpiperazine and aminoalkanol derivatives of 4-azatricyclo[5.2.2.0(2,6)]undecane-3,5,8-trione have been prepared. The synthesized compounds were evaluated for their cytotoxicity and anti-HIV-1 activity in MT-4 cells.
MeSH terms
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Alcohols / chemistry
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Alcohols / pharmacology*
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Alkanes / chemistry
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Alkanes / pharmacology
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Anti-HIV Agents / chemistry*
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Anti-HIV Agents / pharmacology
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Cell Line, Tumor
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Cell Survival / drug effects
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Drug Screening Assays, Antitumor
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Humans
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Piperazines / chemistry
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Piperazines / pharmacology*
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Structure-Activity Relationship
Substances
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Alcohols
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Alkanes
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Anti-HIV Agents
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Piperazines
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undecane