The contributors proposed a differentiated diagnostic technique which included 10 most informative physiologic, anthropometric and biochemical+ indices to provide the most reliable data (95% reliability) on the adaptation and compensatory mechanisms under local vibration and in combination with noise and dust, and with due account of the individual sensitivity to local vibration. Testing of the technique demonstrated its high accuracy in determining the levels of "exhaustion", and of "the normal state" of the adaptation-compensatory mechanisms, and its applicability for vibration disease prognosis in individual++ workers, thus establishing corresponding in preventive medical examinations, occupational selection, preventive measures' planning, and in expert solutions requiring precise diagnostic techniques.