Analysis of the healing process in sinus bone grafting using various grafting materials

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Feb;107(2):204-11. doi: 10.1016/j.tripleo.2008.07.021. Epub 2008 Sep 17.

Abstract

Objectives: The purpose of this study was to compare differences in the healing process in the sinus bone grafting using various grafting materials.

Study design: Maxillary sinus bone grafts were divided into 4 groups according to the graft material used: group I, a mixture of autogenous bone and BioOss (Osteohealth Co., Shirley, NY); group II, a mixture of BioOss and Orthoblast II (Greencross; Isotis); group III, BioOss only; and group IV, synthetic bone, Osteon (Genoss, Korea), only. To evaluate the healing status of the graft surgery, bone specimens were collected from the lateral sinus using a 2.0-mm trephine bur at 4 and 6 months after surgery. Histology of the bone specimens was prepared, and the percentage of newly formed bone fraction, lamellar bone/woven bone ratio (LB/WB), and newly formed bone/graft material ratio (NB/GM) were measured to indicate the suitability of the materials and the healing of the grafts.

Results: The LB/WB ratio and NB/GM ratio were markedly increased at 6 months compared with the values at 4 months. It was observed that good bone healing was achieved even for grafts of xenogeneic bone only or synthetic bone only. Cases grafted with a mixture of allogeneic and xenogeneic bone showed no great advantage regarding bone healing.

Conclusion: The results indicated that grafts of xenogeneic or synthetic bone can be effective for sinus bone grafting.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Animals
  • Bone Density
  • Bone Matrix / transplantation
  • Bone Substitutes*
  • Bone Transplantation / methods*
  • Cattle
  • Dental Implantation, Endosseous
  • Humans
  • Maxillary Sinus / surgery*
  • Oral Surgical Procedures, Preprosthetic / methods*
  • Osseointegration*
  • Time Factors
  • Transplantation, Heterologous

Substances

  • Bone Substitutes