Intramuscular administration of AAV1-lipoprotein lipase S447X lowers triglycerides in lipoprotein lipase-deficient patients

Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2303-4. doi: 10.1161/ATVBAHA.108.175620. Epub 2008 Sep 18.
No abstract available

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dependovirus / genetics
  • Dependovirus / immunology
  • Genetic Therapy / methods*
  • Genetic Vectors
  • Humans
  • Hyperlipoproteinemia Type I / blood
  • Hyperlipoproteinemia Type I / enzymology
  • Hyperlipoproteinemia Type I / genetics
  • Hyperlipoproteinemia Type I / therapy*
  • Injections, Intramuscular
  • Lipoprotein Lipase / genetics*
  • Time Factors
  • Triglycerides / blood

Substances

  • Triglycerides
  • Lipoprotein Lipase