B-alkyl Suzuki couplings for the stereoselective synthesis of substituted pyrans

Chem Commun (Camb). 2008 Sep 28:(36):4294-6. doi: 10.1039/b806898d. Epub 2008 Jul 16.

Abstract

Unprotected homoallylic alcohols can be directly converted to cis-2,6-disubstituted pyrans by palladium catalyzed B-alkyl Suzuki coupling and subsequent Michael addition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Molecular Structure
  • Palladium / chemistry
  • Propanols / chemistry*
  • Pyrans / chemical synthesis*
  • Pyrans / chemistry
  • Stereoisomerism

Substances

  • Propanols
  • Pyrans
  • allyl alcohol
  • Palladium