An unusual case of granulomatous slack skin disease with necrobiosis

Am J Dermatopathol. 2008 Oct;30(5):462-5. doi: 10.1097/DAD.0b013e3181731dfc.

Abstract

Granulomatous slack skin disease (GSS) is a very rare form of T-cell lymphoma, with only 52 cases reported in the literature. In the recent World Health Organization-European Organization for Research and Treatment of Cancer consensus classification GSS is considered to be a variant of mycosis fungoides. We describe a patient with GSS and histologic evidence of necrobiosis, which has not been previously reported.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • CD4-Positive T-Lymphocytes / metabolism
  • CD4-Positive T-Lymphocytes / pathology
  • Humans
  • Leukocyte Common Antigens / metabolism
  • Lymphoma, T-Cell, Cutaneous / complications*
  • Lymphoma, T-Cell, Cutaneous / diagnosis*
  • Lymphoma, T-Cell, Cutaneous / pathology
  • Male
  • Middle Aged
  • Necrobiotic Disorders / complications*
  • Necrobiotic Disorders / diagnosis*
  • Necrobiotic Disorders / pathology
  • Skin Neoplasms / complications*
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / pathology
  • World Health Organization

Substances

  • Leukocyte Common Antigens
  • PTPRC protein, human