Abstract
The US Food and Drug Administration has issued a warning that tipranavir may be associated with increased risk of intracranial hemorrhage. We studied 2 large cohorts to estimate the background rate of intracranial hemorrhage and compared it with rates reported among persons who had been exposed to tipranavir.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adult
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Age Factors
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Anti-HIV Agents / adverse effects*
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California / epidemiology
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Cohort Studies
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Databases, Factual
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Female
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HIV Infections / complications*
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HIV Infections / drug therapy*
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HIV Infections / epidemiology
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Humans
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Intracranial Hemorrhages / epidemiology
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Intracranial Hemorrhages / etiology*
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Male
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Medicaid / statistics & numerical data
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Middle Aged
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Pyridines / adverse effects*
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Pyrones / adverse effects*
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Risk Factors
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Sulfonamides
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United States / epidemiology
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Veterans / statistics & numerical data
Substances
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Anti-HIV Agents
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Pyridines
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Pyrones
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Sulfonamides
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tipranavir