[Effect of rhizoma Zingiberis on anoxic or cooled mice]

Zhongguo Zhong Yao Za Zhi. 1991 Mar;16(3):170-2, 192.
[Article in Chinese]

Abstract

The anti-anoxic experiments have indicated that the petroleum ether extract of Rhizoma Zingiberis can prolong the survival time in mice poisoned by KCN or under the condition of normobaric hypoxia, as well as decapitation-induced gasping duration in mice, but can not prolong the survival time in mice poisoned by NaNO4. The anti-anoxic action might be related to the reduction rate of O2 consumption of the body. The aqueous extract of Rhizoma Zingiberis does not possess the above-mentioned anti-anoxic action. Both extracts do not affect the survival time in cooled mice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cold Temperature / adverse effects*
  • Drugs, Chinese Herbal / pharmacology
  • Drugs, Chinese Herbal / therapeutic use*
  • Drugs, Chinese Herbal / toxicity
  • Female
  • Hypoxia / drug therapy*
  • Male
  • Mice
  • Oxygen Consumption / drug effects
  • Poisoning / drug therapy
  • Potassium Cyanide / poisoning
  • Sodium Nitrite / poisoning

Substances

  • Drugs, Chinese Herbal
  • Sodium Nitrite
  • Potassium Cyanide