High resolution topographical mapping of warm and cold sensitivities

Clin Neurophysiol. 2008 Nov;119(11):2641-6. doi: 10.1016/j.clinph.2008.08.018. Epub 2008 Oct 5.

Abstract

Objective: This study aims to explore the thermal sensitivity distribution (topographical mapping) over the glabrous skin of the hand in males and females.

Methods: Warm (WT) and cold (CT) thresholds were measured in 25 healthy volunteers (12 females), applying a multi-site test of 23 locations on the volar part of the hand.

Results: The palm area was more sensitive than the fingers to both warm (P<0.001) and cold (P<0.001) stimuli. On the palm itself, the proximal part was the most sensitive (P<0.05). Heterogeneity was also found to both warm and cold sensibilities within dermatomes (P<0.05) as well as to cold sensitivity across dermatomes (P<0.001). Females were more sensitive than males to both warm (P<0.001) and cold sensations (P<0.001). In addition, painful components were frequently reported as accompanying warm/cold sensations during mild warming/cooling.

Conclusions: The thermal sensitivity distribution over the glabrous skin of the hand is highly heterogeneous.

Significance: It is appropriate to precisely define testing locations when conducting thermal examinations on the hand.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Analysis of Variance
  • Female
  • Hand / physiology
  • Humans
  • Male
  • Models, Biological
  • Physical Stimulation
  • Sensitivity and Specificity
  • Sensory Thresholds / physiology*
  • Sex Characteristics
  • Skin / innervation*
  • Thermosensing / physiology*
  • Young Adult