Abstract
Lymphomatoid granulomatosis is a rare lymphoproliferative disorder involving the lungs, skin and other organs. Advanced-stage disease does not tend to respond well to cytotoxic chemotherapy and is associated with a poor prognosis. We present a case of successful treatment of relapsed lymphomatoid granulomatosis with bexarotene, a novel retinoid agent.
MeSH terms
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Adult
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Antineoplastic Agents / pharmacology*
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Antineoplastic Combined Chemotherapy Protocols / pharmacology
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Bexarotene
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Cyclophosphamide / pharmacology
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Doxorubicin / pharmacology
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Humans
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Lymphomatoid Granulomatosis / drug therapy*
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Lymphomatoid Granulomatosis / pathology*
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Male
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Prednisolone / pharmacology
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Prognosis
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Recurrence
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Remission Induction
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Retinoids / metabolism
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Tetrahydronaphthalenes / pharmacology*
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Treatment Outcome
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Vincristine / pharmacology
Substances
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Antineoplastic Agents
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Retinoids
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Tetrahydronaphthalenes
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisolone
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Bexarotene