Background: Preoperative chemoradiation for advanced vulvar cancer reduces the tumor size and decreases morbidity from operative resection.
Case: A woman with locally advanced vulvar cancer had no evidence of metastatic disease at presentation. She displayed complete resolution of her vulvar and groin disease but developed early metastatic spread to the lungs and bone.
Conclusion: Despite excellent local control, patients with locally advanced vulvar cancer are at risk for early metastatic spread. The effect of delayed surgical intervention, ifany, is unknown.