Reduced activities of cytochrome P450 1A2 and xanthine oxidase in children with growth hormone deficiency

Clin Pharmacol Ther. 2008 Dec;84(6):674-8. doi: 10.1038/clpt.2008.185. Epub 2008 Oct 8.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Cytochrome P-450 CYP1A2 / genetics
  • Cytochrome P-450 CYP1A2 / metabolism*
  • Cytochrome P-450 CYP2D6 / genetics
  • Cytochrome P-450 CYP2D6 / metabolism
  • Enzyme Activation / genetics
  • Enzyme Activation / physiology*
  • Female
  • Genotype
  • Growth Disorders / enzymology*
  • Growth Disorders / etiology
  • Growth Disorders / physiopathology
  • Growth Hormone / deficiency*
  • Humans
  • Male
  • Probability
  • Reference Values
  • Sensitivity and Specificity
  • Xanthine Oxidase / metabolism*

Substances

  • Growth Hormone
  • Cytochrome P-450 CYP1A2
  • Cytochrome P-450 CYP2D6
  • Xanthine Oxidase