A key factor in successful knee arthroplasty is restoration of correct knee alignment. Although traditional total knee arthroplasty effectively restores alignment, it is unclear whether similar results can be consistently obtained with more conservative procedures. The purpose of this study was to assess alignment after implantation of the Journey Deuce Bi-Compartmental Knee System (Smith & Nephew, Inc, Memphis, Tenn). Mechanical axis was assessed in 137 cases. Preoperatively, 77 (56%) of 137 patients had a mechanical axis passing far medial to the center of the knee, consistent with varus deformity. Postoperatively, 130 (95%) of 137 patients had a mechanical axis passing through the center of the knee. These results suggest that the Journey Deuce Bi-Compartmental Knee System supports correction of varus deformity, previously thought to require total knee arthroplasty or osteotomy.