Use of flow cytometry to monitor Legionella viability

Appl Environ Microbiol. 2008 Dec;74(24):7813-6. doi: 10.1128/AEM.01364-08. Epub 2008 Oct 10.

Abstract

Legionella viability was monitored during heat shock treatment at 70 degrees C by a flow cytometric assay (FCA). After 30 min of treatment, for 6 of the 12 strains tested, the FCA still detected 10 to 25% of cells that were viable but nonculturable (VBNC). These VBNC cells were able to produce ATP and to be resuscitated after culture on amoebae.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amoeba / microbiology
  • Animals
  • Flow Cytometry / methods*
  • Hot Temperature
  • Legionella / growth & development
  • Legionella / physiology*
  • Legionella / radiation effects
  • Microbial Viability