Management of coagulopathy in the patients with multiple injuries: results from an international survey of clinical practice

J Trauma. 2008 Oct;65(4):755-64; discussion 764-5. doi: 10.1097/TA.0b013e318185fa9f.

Abstract

Background: Bleeding is one of the leading causes of preventable death after traumatic injury. Trauma-associated coagulopathy complicates the control of bleeding. The published approaches on the management of this coagulopathy differ significantly.

Methods: A qualitative international survey of clinical practice among senior physicians responsible for the treatment of patients with multiple injuries (Injury Severity Score > or = 16) was conducted to document common practices, highlight the variabilities, and profile the rationale behind existing clinical practices around the world.

Results: Survey results are based on 80 (32%) completed returns, representing 25 countries with 93% of respondents employed by trauma centers and a mean of 20 years clinical experience. There are regional differences in the clinical specialty of physicians responsible for trauma management decisions. Blood loss, temperature, pH, platelets, prothrombin time/INR/activated partial thromboplastin time, and overall clinical assessment, were the most common criteria used to assess coagulopathy. Forty-five percent of respondents claimed to follow a massive transfusion protocol in their institution, 19% reported inconsistent protocol use and 34% do not use a protocol. The management of hypothermia, acidosis, blood products, and adjuvant therapy showed regional as well as institutional variability, and surprisingly few massive transfusion protocols specifically address these issues.

Conclusions: The results of this survey may serve to draw attention to the need for a common definition of coagulopathy and standardized clinical protocols to ensure optimal patient care.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Attitude of Health Personnel
  • Blood Coagulation Disorders / diagnosis
  • Blood Coagulation Disorders / etiology*
  • Blood Coagulation Disorders / mortality
  • Blood Coagulation Disorders / therapy*
  • Blood Transfusion / methods*
  • Blood Transfusion / statistics & numerical data
  • Clinical Competence
  • Early Diagnosis
  • Emergency Treatment / standards
  • Emergency Treatment / trends
  • Female
  • Health Care Surveys
  • Hospital Mortality / trends*
  • Humans
  • Injury Severity Score
  • International Cooperation
  • Male
  • Multiple Trauma / complications*
  • Multiple Trauma / diagnosis
  • Outcome Assessment, Health Care*
  • Patient Care Team / organization & administration
  • Practice Patterns, Physicians'
  • Risk Assessment
  • Surveys and Questionnaires
  • Survival Analysis
  • Transfusion Reaction
  • Trauma Centers
  • Treatment Outcome
  • United States