[Effect of Euro-Collins' or UW solution on the early graft function following cadaveric kidney transplantation]

Nihon Geka Gakkai Zasshi. 1991 Jun;92(6):746-9.
[Article in Japanese]

Abstract

From November 1985 to March 1990, 55 cadaveric kidney transplants were performed under cyclosporine therapy. All kidneys were harvested from non-heart beating donors and cold stored after being flushed with EC solution (Group I, n = 27) or UW solution (Group II, n = 28). Warm ischemic time (min) in groups I and II were 7.1 +/- 3.3 and 6.9 +/- 2.3, respectively. Cold ischemic times (hr) in groups I and II were 6.9 +/- 2.4 and 8.4 +/- 2.8, respectively. Mean numbers of days for postoperative dialysis were 14.0 +/- 7.9 in group I and 7.9 +/- 5.8 in group II (p less than 0.05). One-month creatinine (mg/dl) was 2.9 +/- 2.8 in group I and 1.75 +/- 1.0 in group II (NS). One-month graft survivals (%) in groups I and II were 81.4% and 92.8%, respectively. In conclusion, UW solution has provided beneficial effect of preservation on ischemic damaged kidney and appears to be method of choice in non-heart beating cadaveric kidney transplantation.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adenosine
  • Adult
  • Allopurinol
  • Cadaver
  • Female
  • Glutathione
  • Graft Survival
  • Humans
  • Hypertonic Solutions*
  • Insulin
  • Kidney / physiopathology*
  • Kidney Transplantation* / methods
  • Male
  • Middle Aged
  • Organ Preservation Solutions*
  • Organ Preservation* / methods
  • Postoperative Period
  • Raffinose
  • Retrospective Studies
  • Solutions*

Substances

  • Euro-Collins' solution
  • Hypertonic Solutions
  • Insulin
  • Organ Preservation Solutions
  • Solutions
  • University of Wisconsin-lactobionate solution
  • Allopurinol
  • Glutathione
  • Adenosine
  • Raffinose