The present study was designed to compare the percentage of gutta-percha-filled area (PGFA) achieved in oval-shaped canals after filling by 3 thermoplasticized techniques. Eighty-seven oval-shaped root canals were prepared and root-filled as follows: lateral condensation (n = 20), thermomechanical compaction (n = 20), wave of condensation (n = 20), and Thermafil system (n = 20). A cross section of each tooth was made 5 mm from the apex, and the samples were prepared for microscopic analysis. Digital image measurements of the cross-sectioned area of the canal and the gutta-percha were performed, and the PGFA was calculated. Nonparametric statistical analysis was performed with the Kruskal-Wallis H test and post hoc Dunn test. Overall, PGFAs were variable among the experimental groups, ranging from 37.1%-98.5%, and the pooled data from all techniques had a general mean of 69.6% +/- 18%. Thermafil system, wave of condensation, and thermomechanical compaction produced significantly higher PGFAs than lateral condensation (P < .05); however, no significant differences among these techniques were detected (P > .05). Therefore, a limited ability to fill oval-shaped canals was achieved in the 3 thermoplasticized techniques tested.