Cell surface enzyme attachment is mediated by family 37 carbohydrate-binding modules, unique to Ruminococcus albus

J Bacteriol. 2008 Dec;190(24):8220-2. doi: 10.1128/JB.00609-08. Epub 2008 Oct 17.

Abstract

The rumen bacterium Ruminococcus albus binds to and degrades crystalline cellulosic substrates via a unique cellulose degradation system. A unique family of carbohydrate-binding modules (CBM37), located at the C terminus of different glycoside hydrolases, appears to be responsible both for anchoring these enzymes to the bacterial cell surface and for substrate binding.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bacterial Adhesion
  • Bacterial Proteins / metabolism*
  • Binding Sites
  • Cellulose / metabolism*
  • Cloning, Molecular
  • Glycoside Hydrolases / metabolism*
  • Mutation
  • Protein Binding
  • Ruminococcus / enzymology*
  • Substrate Specificity

Substances

  • Bacterial Proteins
  • Cellulose
  • Glycoside Hydrolases