Identification of Bdellovibrio bacteriovorus HD100 Bd0714 as a Nudix dGTPase

J Bacteriol. 2008 Dec;190(24):8215-9. doi: 10.1128/JB.01009-08. Epub 2008 Oct 17.

Abstract

Bdellovibrio bacteriovorus bacteria are predatory organisms that attack other gram-negative bacteria. Here, we report that Bd0714 is a Nudix dGTPase from B. bacteriovorus HD100 with a substrate specificity similar to that of Escherichia coli MutT and complements an E. coli mutT-deficient strain. We observed different transcription levels of the gene throughout the predator life cycle.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Bdellovibrio / enzymology*
  • Bdellovibrio / genetics
  • Escherichia coli / enzymology
  • Escherichia coli / genetics
  • Escherichia coli Proteins / genetics
  • Escherichia coli Proteins / metabolism
  • Gene Deletion
  • Genes, Bacterial
  • Genetic Complementation Test
  • Molecular Sequence Data
  • Mutation
  • Nudix Hydrolases
  • Phosphoric Monoester Hydrolases / genetics
  • Phosphoric Monoester Hydrolases / metabolism*
  • Pyrophosphatases / genetics
  • Pyrophosphatases / metabolism*
  • Substrate Specificity
  • Transcription, Genetic

Substances

  • Bacterial Proteins
  • Escherichia coli Proteins
  • Phosphoric Monoester Hydrolases
  • Pyrophosphatases
  • mutT protein, E coli