Proliferative lupus nephritis in a patient with systemic lupus erythematosus and longstanding secondary amyloid nephropathy

Jose A Gómez-Puerta; Ricard Cervera; Concepción Moll; Manel Solé; Antonio Collado; Raimon Sanmartí

doi:10.1007/s10067-008-1025-7

Proliferative lupus nephritis in a patient with systemic lupus erythematosus and longstanding secondary amyloid nephropathy

Clin Rheumatol. 2009 Jan;28(1):95-7. doi: 10.1007/s10067-008-1025-7. Epub 2008 Oct 22.

Authors

Jose A Gómez-Puerta¹, Ricard Cervera, Concepción Moll, Manel Solé, Antonio Collado, Raimon Sanmartí

Affiliation

¹ Department of Rheumatology, Hospital Clínic, Barcelona, Spain. [email protected]

PMID: 18941705
DOI: 10.1007/s10067-008-1025-7

Abstract

Secondary amyloidosis is an unusual complication of systemic lupus erythematosus (SLE). We report the case of a 60-year-old woman with SLE and secondary amyloidosis who developed class III proliferative lupus nephritis 13 years after the onset of amyloid nephropathy. The patient was treated with mycophenolate mofetil (1.5 g/day) with a significant improvement in proteinuria.

Publication types

Case Reports

MeSH terms

Amyloid / metabolism
Amyloidosis / complications
Amyloidosis / drug therapy
Amyloidosis / pathology*
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Female
Humans
Kidney / metabolism
Kidney / pathology*
Kidney Glomerulus / metabolism
Kidney Glomerulus / pathology
Lupus Nephritis / complications
Lupus Nephritis / drug therapy
Lupus Nephritis / pathology*
Middle Aged
Mycophenolic Acid / analogs & derivatives
Mycophenolic Acid / therapeutic use
Proteinuria / drug therapy
Treatment Outcome

Substances

Amyloid
Anti-Inflammatory Agents, Non-Steroidal
Mycophenolic Acid