Five-millimeter and smaller embryos without embryonic cardiac activity: outcomes in women with vaginal bleeding

J Ultrasound Med. 2008 Nov;27(11):1559-61. doi: 10.7863/jum.2008.27.11.1559.

Abstract

Objective: The purpose of this study was to assess outcomes in embryos with a crown-rump length (CRL) of 5 mm or less without embryonic cardiac activity (ECA) among pregnant women with vaginal bleeding in the first trimester.

Methods: A retrospective study of all first-trimester sonograms in women with vaginal bleeding from 1999 to 2002 was conducted.

Results: Thirty-seven embryos without detectable ECA that had a CRL of 5 mm or less were identified. All resulted in pregnancy failure. The breakdown of these embryos by CRL was as follows: 13 were 5 mm; 10 ranged from 4 to 4.9 mm; 11 ranged from 3 to 3.9 mm; and 3 ranged from 2 to 2.9 mm.

Conclusions: In pregnant women with vaginal bleeding, embryos of 5 mm and smaller without a heartbeat all resulted in pregnancy failure.

MeSH terms

  • Echocardiography / methods*
  • Embryo, Mammalian / diagnostic imaging*
  • Female
  • Fetal Death / diagnostic imaging*
  • Fetal Heart / diagnostic imaging*
  • Humans
  • Pregnancy
  • Pregnancy Outcome*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Ultrasonography, Prenatal / methods*
  • Uterine Hemorrhage / complications
  • Uterine Hemorrhage / diagnostic imaging*