Abstract
A 59-year-old man with long-standing rheumatoid arthritis (RA) developed renal dysfunction, proteinuria and hematuria. Neither gold nor penicillamine had been given. Light microscopy of a renal biopsy specimen revealed membranous nephropathy with crescents of various stages. The possible pathogenesis of such an unusual combination of membranous nephropathy and crescents in RA is discussed.
MeSH terms
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Arthritis, Rheumatoid / complications*
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Complement C3 / metabolism
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Glomerulonephritis, Membranous / etiology*
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Glomerulonephritis, Membranous / immunology
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Glomerulonephritis, Membranous / pathology
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Humans
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Immunoglobulin G / metabolism
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Immunoglobulin M / metabolism
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Kidney Glomerulus / ultrastructure
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Male
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Middle Aged
Substances
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Complement C3
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Immunoglobulin G
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Immunoglobulin M