Abstract
Venous thromboembolism is a rare condition in children, but the incidence appears to be increasing. Newborns and teenagers are at the highest risk of thrombosis, which is often triggered by a combination of risk factors, in particular: infection, central venous line or chemotherapy. The impact of thrombophilia is uncertain. International guidelines recommend screening for thrombophilia as part of the diagnostic set-up in children with thrombosis. Treatment of paediatric thrombosis with low-molecular-weight heparin appears safe, but the effectiveness remains to be established.
MeSH terms
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Adolescent
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Child
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Fibrinolytic Agents / therapeutic use
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Heparin, Low-Molecular-Weight / therapeutic use
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Humans
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Incidence
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Infant, Newborn
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Risk Factors
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Sinus Thrombosis, Intracranial / drug therapy
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Sinus Thrombosis, Intracranial / epidemiology
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Sinus Thrombosis, Intracranial / etiology
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Thromboembolism* / drug therapy
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Thromboembolism* / epidemiology
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Thromboembolism* / etiology
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Thrombophilia / complications
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Thrombophilia / diagnosis
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Venous Thrombosis* / drug therapy
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Venous Thrombosis* / epidemiology
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Venous Thrombosis* / etiology
Substances
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Fibrinolytic Agents
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Heparin, Low-Molecular-Weight