Abstract
MrtR, a LuxR homolog in Mesorhizobium tianshanense, is important for symbiosis. We found that MrtR requires its cognate N-acylhomoserine lactone for forming dimers, binding to a single DNA site and activating the downstream promoter. However, MrtR is able to fold independently of its ligand.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Agrobacterium tumefaciens / genetics
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Bacterial Proteins / metabolism
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Base Sequence
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DNA, Bacterial / genetics
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DNA-Binding Proteins / genetics
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DNA-Binding Proteins / physiology*
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Dimerization
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Molecular Sequence Data
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Mutagenesis
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Plasmids
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Protein Folding
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Quorum Sensing / genetics
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Quorum Sensing / physiology*
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Repressor Proteins / genetics
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Repressor Proteins / physiology*
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Rhizobium / physiology*
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Symbiosis / physiology
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Trans-Activators / genetics
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Trans-Activators / physiology*
Substances
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Bacterial Proteins
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DNA, Bacterial
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DNA-Binding Proteins
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Repressor Proteins
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Trans-Activators
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LuxR autoinducer binding proteins