Pathways of proliferation: new targets to inhibit the growth of vascular smooth muscle cells

Circ Res. 2008 Nov 7;103(10):1047-9. doi: 10.1161/CIRCRESAHA.108.188003.
No abstract available

Publication types

  • Comment
  • Editorial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Cells, Cultured
  • Cyclin-Dependent Kinase Inhibitor p16 / genetics
  • Cyclin-Dependent Kinase Inhibitor p16 / metabolism*
  • Dyslipidemias / enzymology
  • Dyslipidemias / genetics
  • E2F1 Transcription Factor / genetics
  • E2F1 Transcription Factor / metabolism
  • Enzyme Activation / drug effects
  • Enzyme Activation / physiology
  • G1 Phase / physiology*
  • Gene Expression Regulation, Enzymologic / drug effects
  • Gene Expression Regulation, Enzymologic / physiology*
  • Mice
  • Mitogens / metabolism
  • Mitogens / pharmacology
  • Myocytes, Smooth Muscle / enzymology*
  • PPAR alpha / agonists
  • PPAR alpha / metabolism*
  • Promoter Regions, Genetic / physiology
  • Rats
  • Retinoblastoma-Like Protein p107 / genetics
  • Retinoblastoma-Like Protein p107 / metabolism
  • Retinoblastoma-Like Protein p130 / genetics
  • Retinoblastoma-Like Protein p130 / metabolism
  • S Phase / physiology*
  • Telomerase / biosynthesis*
  • Telomerase / genetics
  • Transcription, Genetic / drug effects
  • Transcription, Genetic / physiology

Substances

  • Cyclin-Dependent Kinase Inhibitor p16
  • E2F1 Transcription Factor
  • E2f1 protein, mouse
  • E2f1 protein, rat
  • Mitogens
  • PPAR alpha
  • Rbl1 protein, mouse
  • Rbl2 protein, mouse
  • Rbl2 protein, rat
  • Retinoblastoma-Like Protein p107
  • Retinoblastoma-Like Protein p130
  • Telomerase
  • Tert protein, mouse