Improved NMR methods for the direct 13C-satellite-selective excitation in overlapped 1H-NMR spectra

Magn Reson Chem. 2009 Feb;47(2):121-32. doi: 10.1002/mrc.2363.

Abstract

Improved pulsed-field gradient echo methods are presented and discussed for the direct selective excitation of the (13)C-satellite lines in overcrowded (1)H NMR spectra of small molecules. Sensitivity enhancements in (13)C spin-state selection can be achieved by combining multiple-proton-frequency excitation and Hadamard phase encoding. Several satellite-selective (SATSEL) NMR experiments are proposed and exemplified by measuring the sign and the magnitude of small, long-range proton-carbon coupling constants for (1)H resonances showing several levels of signal overlapping.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon Isotopes*
  • Magnetic Resonance Spectroscopy / instrumentation*
  • Magnetic Resonance Spectroscopy / methods
  • Magnetic Resonance Spectroscopy / standards
  • Models, Theoretical
  • Protons

Substances

  • Carbon Isotopes
  • Protons