Iatrogenic Cushing syndrome after epidural triamcinolone injections in an HIV type 1-infected patient receiving therapy with ritonavir-lopinavir

Clin Infect Dis. 2008 Dec 15;47(12):e97-9. doi: 10.1086/593314.

Abstract

We report the first case of a human immunodeficiency virus type 1 (HIV-1)-infected individual receiving combination antiretroviral therapy, which included ritonavir, who developed Cushing syndrome with profound complications after epidural triamcinolone injections. This case highlights the potential of ritonavir interactions even with local injections of a corticosteroid.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Cushing Syndrome*
  • Drug Interactions
  • HIV Infections / complications*
  • HIV Infections / drug therapy*
  • HIV-1 / isolation & purification
  • Humans
  • Iatrogenic Disease*
  • Lopinavir
  • Male
  • Pyrimidinones / therapeutic use*
  • Ritonavir / therapeutic use*
  • Triamcinolone / administration & dosage*
  • Triamcinolone / adverse effects*

Substances

  • Pyrimidinones
  • Triamcinolone
  • Lopinavir
  • Ritonavir