4-(pyridin-2-yl)thiazol-2-yl thioglycosides as bidentate ligands for oligosaccharide synthesis via temporary deactivation

Chem Commun (Camb). 2008 Nov 21:(43):5633-5. doi: 10.1039/b810569c. Epub 2008 Oct 1.

Abstract

This study focusses on a new concept for oligosaccharide synthesis based on 4-(pyridin-2-yl)thiazol-2-yl thioglycosides that can either act as effective glycosyl donors or can be deactivated by stable bidentate complexation with palladium(II) bromide.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bromides / chemistry
  • Carbohydrate Sequence
  • Crystallography, X-Ray
  • Ligands
  • Models, Molecular
  • Molecular Sequence Data
  • Molecular Structure
  • Oligosaccharides / chemical synthesis*
  • Oligosaccharides / chemistry
  • Palladium / chemistry
  • Thioglycosides / chemistry*

Substances

  • Bromides
  • Ligands
  • Oligosaccharides
  • Thioglycosides
  • Palladium