Identification of a new HLA DRB1 allele (HLA-DRB1*1167) in a potential hematopoietic stem cell donor from Iraqi Kurdistan

Tissue Antigens. 2009 Jan;73(1):80-1. doi: 10.1111/j.1399-0039.2008.01163.x. Epub 2008 Oct 24.

Abstract

High-resolution polymerase chain reaction sequence-specific primer typing and sequence-based typing of the human leukocyte antigen (HLA) gene DRB1 in a potential hematopoietic stem cell donor of Kurdish ethnicity revealed a new allelic variant of HLA-DRB1*11. The sequence was named DRB1*1167, and comparison with previously described DRB1 alleles demonstrated a mixed pattern shared with some DRB1*08 alleles.

MeSH terms

  • Alleles
  • Amino Acid Sequence
  • Base Sequence
  • HLA-DR Antigens / genetics*
  • HLA-DRB1 Chains
  • Hematopoietic Stem Cells
  • Humans
  • Iraq
  • Living Donors
  • Molecular Sequence Data
  • Sequence Alignment

Substances

  • HLA-DR Antigens
  • HLA-DRB1 Chains
  • HLA-DRB1*11:67 antigen