Abstract
The combined systemic and topical administration of voriconazole has successfully been used to treat keratomycosis. Because no voriconazole eye drop product is commercially available, we prepared a sterile eye drop solution (10 mg/ml). Voriconazole remains stable over 30 days, providing an eye drop solution suitable for use for the topical treatment of fungal keratitis.
MeSH terms
-
Antifungal Agents / administration & dosage
-
Antifungal Agents / pharmacology*
-
Chemistry, Pharmaceutical
-
Drug Compounding
-
Drug Stability
-
Excipients
-
Hydrogen-Ion Concentration
-
Ophthalmic Solutions
-
Pyrimidines / administration & dosage
-
Pyrimidines / pharmacology*
-
Triazoles / administration & dosage
-
Triazoles / pharmacology*
-
Voriconazole
Substances
-
Antifungal Agents
-
Excipients
-
Ophthalmic Solutions
-
Pyrimidines
-
Triazoles
-
Voriconazole