The human ability to focus memory retrieval operations on a particular list, episode or memory structure has not been fully appreciated or documented. In Experiment 1-3, we make it increasingly difficult for participants to switch between a less recent list (multiple study opportunities), and a more recent list (single study opportunity). Task performance was good, although there was a cost associated with switching. In Experiment 4, list-specific learning experiences were used to create a generalized memory as a step towards semantic memory. List-specific memories intruded during attempts to retrieve the generalized memory and the generalized memory enhanced list-specific performance. The generalized memory also intruded in a free-association task. We propose that a hierarchy of contexts and control operations underlie the human ability to access different memory structures and that there is no sharp discontinuity in the control operations needed to access list-specific, generalized, and semantic memories.