Neuropathic pain in people treated for multibacillary leprosy more than ten years previously

Lepr Rev. 2008 Sep;79(3):270-6.

Abstract

Objectives: To identify patients with typical symptoms of neuropathic pain in a well-defined cohort of multibacillary patients being followed up as part of a relapse study in Ethiopia; to identify risk factors for the development of neuropathic pain.

Design: 96 patients who had completed MDT more than 10 years previously participated in the study, through a questionnaire.

Results: 28 (29%) had symptoms of neuropathic pain and it was reported as severe in 12. Because the past history of these subjects is well documented, a risk factor analysis was carried out. The presence of leprosy-related impairment was the only significant risk factor for neuropathic pain that was identified.

Conclusions: Neuropathic pain is an important problem in a proportion of people previously treated for leprosy. Further research into the management of the condition is required.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Cohort Studies
  • Drug Therapy, Combination
  • Ethiopia
  • Female
  • Humans
  • Leprostatic Agents / therapeutic use*
  • Leprosy / complications*
  • Leprosy / drug therapy*
  • Male
  • Middle Aged
  • Pain Measurement*
  • Peripheral Nervous System Diseases / etiology
  • Peripheral Nervous System Diseases / physiopathology*
  • Recurrence
  • Risk Factors
  • Severity of Illness Index
  • Surveys and Questionnaires
  • Time Factors
  • Young Adult

Substances

  • Leprostatic Agents