Minced articular cartilage--basic science, surgical technique, and clinical application

Sports Med Arthrosc Rev. 2008 Dec;16(4):217-20. doi: 10.1097/JSA.0b013e31818e0e4a.

Abstract

Minced articular cartilage procedures are attractive surgical approaches for repairing articular cartilage, as they are 1-staged, autologous, and inserted on a carrier that can potentially be placed arthroscopically. The principle of mincing the autologous donor cartilage is to create a larger surface area for cartilage expansion. Placement on a scaffold carrier allows for a chondro-inductive and chondro-conductive milieu. Early animal and preclinical models have demonstrated hyaline-like tissue repair. Further work needs to be conducted in this promising approach.

Publication types

  • Review

MeSH terms

  • Animals
  • Arthroscopy / methods*
  • Biocompatible Materials
  • Cartilage Diseases / surgery*
  • Cartilage, Articular / surgery
  • Cartilage, Articular / transplantation*
  • Cattle
  • Chondrocytes / transplantation
  • Clinical Trials as Topic
  • Female
  • Graft Rejection
  • Graft Survival
  • Humans
  • Male
  • Minimally Invasive Surgical Procedures
  • Prognosis
  • Sensitivity and Specificity
  • Tissue Engineering / methods*
  • Tissue Scaffolds
  • Tissue Transplantation / methods*
  • Transplantation, Autologous

Substances

  • Biocompatible Materials