Abstract
Nephrogenic systemic fibrosis is a disabling progressive condition that is being reported with increased frequency in patients with kidney disease. Treatment is extremely limited and largely supportive. We report a case of severe nephrogenic systemic fibrosis in a dialysis patient exposed to multiple doses of gadolinium who improved clinically and histologically with treatment with imatinib.
MeSH terms
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Benzamides
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Contrast Media / adverse effects
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Female
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Gadolinium / adverse effects
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Humans
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Imatinib Mesylate
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Kidney Failure, Chronic
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Middle Aged
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Nephrogenic Fibrosing Dermopathy / chemically induced
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Nephrogenic Fibrosing Dermopathy / drug therapy*
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Piperazines / therapeutic use*
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Protein Kinase Inhibitors / therapeutic use*
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Pyrimidines / therapeutic use*
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Renal Dialysis
Substances
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Benzamides
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Contrast Media
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Piperazines
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Protein Kinase Inhibitors
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Pyrimidines
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Imatinib Mesylate
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Gadolinium