Genetic association analysis with FAMHAP: a major program update

Bioinformatics. 2009 Jan 1;25(1):134-6. doi: 10.1093/bioinformatics/btn581. Epub 2008 Nov 9.

Abstract

FAMHAP is an established software for haplotype association analysis of nuclear families. We have released a major update that comprises various new features for case-control data. Furthermore, weprovide an additional program runFamhap that allows users to start the same method repeatedly for varying sets of genetic markers. In addition, a platform-independent graphical user interface (GUI) was developed to simplify the usage of both FAMHAP and runFamhap. The runFamhap program greatly facilitates the application of FAMHAP to genome-wide association studies (GWAS) and supports flexible genome-wide haplotype analysis. As an example, we describe application to HapMap data.

Availability: The software is available at http://famhap.meb.uni-bonn.de

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology / methods*
  • Genome-Wide Association Study*
  • Haplotypes
  • Humans
  • Software*