Abstract
Salmonella genomic island 1 was identified for the first time in Salmonella enterica serovar Virchow isolated from humans in Taiwan. The complex class 1 integron conferring multidrug resistance was shown to be inserted within open reading frame (ORF) S023 and contains for the first time a partial transpositional module. The 5-bp target duplication flanking the complex integron suggests that its insertion in ORF S023 was by transposition.
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Chloramphenicol / pharmacology
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Chromosomes, Bacterial / genetics
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Drug Resistance, Multiple, Bacterial
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Genes, Bacterial / genetics*
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Genomic Islands / genetics*
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Humans
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Integrons / genetics*
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Reverse Transcriptase Polymerase Chain Reaction
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Salmonella Infections / microbiology
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Salmonella enterica / drug effects
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Salmonella enterica / genetics*
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Taiwan
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Thiamphenicol / analogs & derivatives
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Thiamphenicol / pharmacology
Substances
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Anti-Bacterial Agents
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Chloramphenicol
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florfenicol
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Thiamphenicol