Spectral-domain optical coherence tomography images of inner/outer segment junctions and macular hole surgery outcomes

Graefes Arch Clin Exp Ophthalmol. 2009 Mar;247(3):325-30. doi: 10.1007/s00417-008-0999-9. Epub 2008 Nov 19.

Abstract

Background: To evaluate the ability of spectral-domain optical coherence tomography (SD-OCT) images of the inner/outer segment (IS/OS) junction to predict macular hole surgery outcomes.

Methods: Fifty-four eyes in 53 patients with idiopathic macular holes were studied. Postoperative visual acuity and SD-OCT images of the fovea were examined before and 12 months after surgery. The total area and the maximum length of the IS/OS junction defect were measured.

Results: The macular holes were successfully closed in all the eyes included in this series. The mean log MAR visual acuity improved significantly from 0.67 +/- 0.25 preoperatively to 0.16 +/- 0.22 postoperatively (p < 0.001). The mean total area and maximum length of the IS/OS junction defect at 12 months after surgery were 10,185 +/- 1,537 microm(2) and 100.5 +/- 10.4 microm respectively; these values were significantly negatively correlated with the postoperative visual acuity.

Conclusion: SD-OCT is useful for quantitatively measuring IS/OS junction defects. The postoperative IS/OS junction may play an important role in visual recovery after macular hole surgery.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retinal Perforations / diagnosis*
  • Retinal Perforations / surgery*
  • Retinal Photoreceptor Cell Inner Segment / pathology*
  • Retinal Photoreceptor Cell Outer Segment / pathology*
  • Tomography, Optical Coherence / methods*
  • Treatment Outcome
  • Visual Acuity / physiology