Abstract
During 6 months, we obtained Enterobacteriaceae isolates from patients with gram-negative bacteremia at a 1,250-bed teaching hospital in St. Louis, MO, and compared carbapenem susceptibilities with the presence of bla(KPC), a transferable carbapenemase gene. Three (1.2%) out of 243 isolates were bla(KPC) positive. Ertapenem nonsusceptibility had a low positive predictive value.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Aged
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Anti-Bacterial Agents / pharmacology*
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Bacteremia / microbiology*
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Bacterial Proteins / genetics*
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Carbapenems / pharmacology*
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Enterobacteriaceae / enzymology*
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Enterobacteriaceae / isolation & purification
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Enterobacteriaceae Infections / microbiology*
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Ertapenem
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Humans
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Microbial Sensitivity Tests
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Middle Aged
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Missouri
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Predictive Value of Tests
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beta-Lactam Resistance*
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beta-Lactamases / genetics*
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beta-Lactams / pharmacology
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Carbapenems
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beta-Lactams
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beta-Lactamases
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carbapenemase
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Ertapenem