Cross-reactivity of Paracoccidioides brasiliensis, Histoplasma capsulatum, and Cryptococcus species in the commercial Platelia Aspergillus enzyme immunoassay

Clin Vaccine Immunol. 2009 Jan;16(1):132-3. doi: 10.1128/CVI.00310-08. Epub 2008 Nov 19.

Abstract

Cross-reactivity in the Platelia Aspergillus enzyme immunoassay was evaluated using 120 sera from patients with paracoccidioidomycosis, histoplasmosis, and cryptococcosis. At a cutoff value of 0.5, positivity rates were 50%, 67%, and 50%, respectively. The implications for these findings are discussed.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens, Fungal / blood
  • Aspergillosis / diagnosis*
  • Aspergillus / immunology*
  • Cross Reactions*
  • Cryptococcus / immunology*
  • Histoplasma / immunology*
  • Humans
  • Immunoenzyme Techniques / methods
  • Paracoccidioides / immunology*
  • Sensitivity and Specificity

Substances

  • Antigens, Fungal