Recurrent ameloblastoma following osseous reconstruction--a review of twenty years

J Craniomaxillofac Surg. 2009 Jan;37(1):36-41. doi: 10.1016/j.jcms.2008.07.009. Epub 2008 Nov 20.

Abstract

Background: The adequate therapy of ameloblastoma may require a compromise between the least destructive treatment possible of a benign tumour and a sufficiently radical method to prevent recurrences. Frequently recurrences appear after 10 years or longer, therefore regular follow-up visits even after more than 5 years are recommended. The primary reconstruction of bones and/or soft tissues, which is likely to be performed especially for benign processes is threatened by recurrences.

Methods: A retrospective analysis of our patient group during the past 20 years has shown that a differentiated pretherapeutic securing of the histology as well as a radical surgical policy are the most important criteria, influencing the likelihood of recurrences. Three representative case histories are described below.

Results: The rate of cumulative relapses with regard to various observation time amounted to 17% after 5 years and 19% after 10 years, respectively.

Conclusion: Ameloblastomas carry a certain risk of developing local recurrences depending on histology and the type of surgical treatment. Long-term follow-up should be arranged.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Ameloblastoma / pathology*
  • Ameloblastoma / prevention & control
  • Ameloblastoma / surgery
  • Bone Transplantation
  • Child
  • Disease-Free Survival
  • Female
  • Follow-Up Studies
  • Humans
  • Jaw Neoplasms / pathology*
  • Jaw Neoplasms / surgery
  • Male
  • Mandibular Neoplasms / pathology
  • Mandibular Neoplasms / surgery
  • Maxillary Neoplasms / pathology
  • Maxillary Neoplasms / surgery
  • Middle Aged
  • Neoplasm Recurrence, Local / pathology*
  • Neoplasm Recurrence, Local / prevention & control
  • Neoplasm Recurrence, Local / surgery
  • Plastic Surgery Procedures*
  • Retrospective Studies
  • Surgical Flaps
  • Young Adult